Antenatal Glucocorticoid Therapy for Fetal Heart Development
نویسندگان
چکیده
منابع مشابه
Antenatal glucocorticoid therapy for fetal heart development.
itochondria occupy approximately 30% cell volume of cardiac myocytes. They are key organelles that orchestrate cardiac function under physiological and pathological conditions. Their principal function is ATP production via their electron transport system. However, recent studies indicate that mitochondria have additional roles in oxidative stress production,1 intracellular Ca2+ handling,2 and ...
متن کاملAntenatal Corticosteroid Therapy for Fetal Maturation.
OBJECTIVES To assess the benefits and risks of antenatal corticosteroid therapy for fetal maturation. OPTIONS To administer antenatal corticosteroids or not to women at risk of preterm birth. OUTCOMES Perinatal morbidity, including: respiratory distress syndrome, intraventricular hemorrhage, infection, adrenal suppression, somatic and brain growth; perinatal mortality; and maternal morbidit...
متن کاملThe fetal respiratory system as target for antenatal therapy
The widespread use of prenatal ultrasound has made the fetus a patient. A number of conditions diagnosed as such may require therapy prior to birth. Herein we describe past, current and potential future procedures designed to treat pulmonary conditions in the antenatal period. When congenital cystic adenomatoid malformation (CCAM) is -associated with fetal hydrops, treatment is required. Prior ...
متن کاملAntenatal glucocorticoid therapy: a caveat to the applause.
Pre-term delivery creates a series of untimely challenges for the newborn, with the lungs, in particular, poorly prepared for independent existence ex utero. In many mammals, rising glucocorticoid levels in the fetal circulation just before birth act as a physiological stimulus to the development of immature systems, inducing critical events such as pulmonary surfactant production. A number of ...
متن کاملAntenatal Glucocorticoid Treatment Affects Hippocampal Development in Mice
Synthetic glucocorticoids are administered to pregnant women at risk for preterm delivery, to enhance fetal lung maturation. The benefit of this treatment is well established, however caution is necessary because of possible unwanted side effects on development of different organ systems, including the brain. Actions of glucocorticoids are mediated by corticosteroid receptors, which are highly ...
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ژورنال
عنوان ژورنال: Circulation Journal
سال: 2010
ISSN: 1346-9843,1347-4820
DOI: 10.1253/circj.cj-09-0827